by Eva Huala
“Neither snow nor rain nor heat nor gloom of night stays these couriers from the swift completion of their appointed rounds”
(Inscription on the James Farley Post Office in New York City)
The Plant Working Group project is progressing well! We met on May 1-2 in Ames Iowa (thanks to Rex, Carolyn and Steven for hosting us on campus!) Thanks to our local team we got a lot done and managed to have plenty of fun too, in spite of the surprise spring snowstorm that dropped 2 or 3 inches of snow in Ames.
Since then, we have been iterating on our phenotype annotation files with Anika and Ramona’s help to get them to conform to our agreed-on standards. Anika has been kind enough to implement a series of automated file checks to ensure that we are using the PO, GO, ChEBI, PATO and EO ontologies consistently and correctly to describe our phenotypes. We’re also working on the early stages of an analysis of the full phenotype annotation set which it appears will include 6400 phenotype annotation statements made to 2750 mutant genes across 6 plant species! The exciting analysis possibilities include investigating the extent to which a mutant phenotype can be predicted from protein similarity or vice versa, and whether this can be used as a basis for selecting candidate genes underlying QTL or genetic loci.