Homology-based transferal stays the key strategy to computational protein operate annotations, nevertheless it turns into more and more unreliable when the sequence identification between question and template decreases under 30%. We suggest a novel pipeline, MetaGO, to infer Gene Ontology attributes of proteins by combining sequence homology-based annotation with low-resolution construction prediction and comparability, and accomplice’s homology-based protein-protein community mapping. The pipeline was examined on a large-scale set of 1000 non-redundant proteins from the CAFA3 experiment.
Underneath the stringent benchmark situations the place templates with >30% sequence identification to the question are excluded, MetaGO achieves common F-measures of 0.487, 0.408, and 0.598, for Molecular Operate, Organic Course of, and Mobile Element, respectively, that are considerably greater than these achieved by different state-of-the-art operate annotations strategies. Detailed information evaluation exhibits that the key benefit of the MetaGO lies within the new purposeful homolog detections from accomplice’s homology-based community mapping and structure-based native and international construction alignments, the boldness scores of which will be optimally mixed via logistic regression.
Rabbit Anti BSA | |||
EnoGene | |||
rabbit anti mouse | |||
Clemente Associates LLC | |||
Rabbit anti Bovine | |||
EnoGene | |||
Rabbit anti alpaca IgG rabbit pAb | |||
EnoGene | |||
Rabbit anti alpaca IgG rabbit pAb | |||
EnoGene |
Analyzing consumer interactions with biomedical ontologies: A visible perspective.
Biomedical ontologies are giant: A number of ontologies within the BioPortal repository include hundreds and even lots of of hundreds of entities. The event and upkeep of such giant ontologies is tough. To assist ontology authors and repository builders of their work, it’s essential to enhance our understanding of how these ontologies are explored, queried, reused, and utilized in downstream functions by biomedical researchers. We current an exploratory empirical evaluation of consumer actions within the BioPortal ontology repository by analyzing BioPortal interplay logs throughout totally different entry modes over a number of years. We examine how customers of BioPortal question and seek for ontologies and their courses, how they discover the ontologies, and the way they reuse courses from totally different ontologies.
MARK Antibody | |||
SAB | |||
MARK Antibody | |||
SAB | |||
MARK Antibody | |||
SAB | |||
MARK Antibody | |||
EnoGene | |||
MARK Antibody | |||
EnoGene |
Moreover, via three real-world situations, we not solely analyze the utilization of ontologies for annotation duties but in addition evaluate it to the searching and querying behaviors of BioPortal customers. For our investigation, we use a number of totally different visualization strategies. To examine giant quantities of interplay, reuse, and real-world utilization information at a look, we make use of and lengthen PolygOnto, a visualization technique that has been efficiently used to investigate reuse of ontologies in earlier work. Our outcomes present that exploration, question, reuse, and precise utilization behaviors not often align, suggesting that totally different customers are inclined to discover, question and use totally different elements of an ontology. Lastly, we spotlight and focus on variations and commonalities amongst customers of BioPortal.
Recombinant Humanp21 Recombinant Protein | |||
ProSci | |||
TAGLN Recombinant Protein (Rat) (Recombinant- Tag) | |||
ABM | |||
TAGLN2 Recombinant Protein (Rat) (Recombinant Tag) | |||
ABM | |||
TAGLN3 Recombinant Protein (Rat) (Recombinant Tag) | |||
ABM | |||
TAGLN3 Recombinant Protein (Rat) (Recombinant Tag) | |||
ABM |
Deep Studying Meets Biomedical Ontologies: Data Embeddings for Epilepsy.
Whereas biomedical ontologies have historically been used to information the identification of ideas or relations in biomedical information, current advances in deep studying are in a position to seize high-quality data from textual information and characterize it in graphical constructions. Versus the top-down methodology used within the era of ontologies, which begins with the principled design of the higher ontology, the bottom-up methodology enabled by deep studying encodes the chance that ideas share sure relations, as evidenced by information.
Recombinant Humanp21 Recombinant Protein | |||
92-035 | |||
TAGLN Recombinant Protein (Rat) (Recombinant- Tag) | |||
RP232205 | |||
TAGLN2 Recombinant Protein (Rat) (Recombinant Tag) | |||
RP232208 | |||
TAGLN3 Recombinant Protein (Rat) (Recombinant Tag) | |||
RP232211 | |||
TAGLN3 Recombinant Protein (Rat) (Recombinant Tag) | |||
RP232214 |
H2B Antibody Antibody | |||
E11-184659 | |||
Lck antibody Antibody | |||
GWB-250026 | |||
anti- Antibody^Polyclonal antibody control antibody | |||
LSMab09882 | |||
CD11b Antibody Antibody | |||
E19-2911-1 | |||
CD11b Antibody Antibody | |||
E19-2911-2 |
On this paper, we current a data illustration produced by deep studying strategies, known as Medical Data Embeddings (MKE), that encode medical ideas associated to the research of epilepsy and the relations between them. Most of the epilepsy-relevant medical ideas from MKE aren’t but obtainable in present biomedical ontologies, however are talked about in huge collections of epilepsy-related medical information which additionally indicate their relationships. The analysis of the MKE signifies excessive accuracy of the medical ideas routinely recognized from scientific textual content in addition to promising outcomes by way of correctness and completeness of relations produced by deep studying.
H2B Antibody Antibody |
Lck antibody Antibody |
Ontology for Semantic Information Integration within the Area of IT Benchmarking.
A site-specific ontology for IT benchmarking has been developed to bridge the hole between a scientific characterization of IT providers and their data-based valuation. Since data is mostly collected throughout a benchmark train utilizing questionnaires on a broad vary of subjects, akin to worker prices, software program licensing prices, and portions of {hardware}, it’s generally saved as pure language textual content; thus, this data is saved in an intrinsically unstructured kind.
Though these information kind the premise for figuring out potentials for IT value reductions, neither a uniform description of any measured parameters nor the connection between such parameters exists. Therefore, this work proposes an ontology for the area of IT benchmarking, obtainable at https://w3id.org/bmontology. The design of this ontology relies on necessities primarily elicited from a site evaluation, which considers analyzing paperwork and interviews with representatives from Small- and Medium-Sized Enterprises and Data and Communications Know-how firms over the past eight years.
ERC1 Protein Vector (Rat) (pPB-C-His) |
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PV266474 | ABM | 500 ng | EUR 1399.2 |
ERC1 Protein Vector (Rat) (pPB-N-His) |
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PV266475 | ABM | 500 ng | EUR 1399.2 |
ERC1 Protein Vector (Rat) (pPM-C-His) |
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PV266477 | ABM | 500 ng | EUR 1399.2 |
ERC2 Protein Vector (Rat) (pPB-C-His) |
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PV266478 | ABM | 500 ng | EUR 1399.2 |
ERC2 Protein Vector (Rat) (pPB-N-His) |
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PV266479 | ABM | 500 ng | EUR 1399.2 |
ERC2 Protein Vector (Rat) (pPM-C-His) |
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PV266481 | ABM | 500 ng | EUR 1399.2 |
ERCC1 Recombinant Protein (Rat) |
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RP199859 | ABM | 100 ug | Ask for price |
ERCC2 Recombinant Protein (Rat) |
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RP199862 | ABM | 100 ug | Ask for price |
ERCC3 Recombinant Protein (Rat) |
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RP199865 | ABM | 100 ug | Ask for price |
ERCC8 Recombinant Protein (Rat) |
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RP199874 | ABM | 100 ug | Ask for price |
C-ERC ELISA KIT|Human |
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EF008507 | Lifescience Market | 96 Tests | EUR 826.8 |
Rat BMP-2 protein |
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PRP120126-100ug | Abbkine | 100 μg | EUR 1559 |
Description: Rat BMP-2 protein, expressed in E. coli |
Rat BMP-2 protein |
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PRP120126-1mg | Abbkine | 1 mg | EUR 7809 |
Description: Rat BMP-2 protein, expressed in E. coli |
Rat BMP-2 protein |
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PRP120126-20ug | Abbkine | 20 μg | EUR 519 |
Description: Rat BMP-2 protein, expressed in E. coli |
ERCC1 Protein Vector (Rat) (pPM-C-HA) |
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PV266484 | ABM | 500 ng | EUR 723.6 |
ERCC2 Protein Vector (Rat) (pPM-C-HA) |
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PV266488 | ABM | 500 ng | EUR 1399.2 |
ERCC3 Protein Vector (Rat) (pPM-C-HA) |
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PV266492 | ABM | 500 ng | EUR 1399.2 |
ERCC5 Protein Vector (Rat) (pPM-C-HA) |
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PV266496 | ABM | 500 ng | EUR 1399.2 |
ERCC6 Protein Vector (Rat) (pPM-C-HA) |
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PV266500 | ABM | 500 ng | EUR 1429.2 |
ERCC8 Protein Vector (Rat) (pPM-C-HA) |
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PV266504 | ABM | 500 ng | EUR 723.6 |
ERCC1 Protein Vector (Rat) (pPB-C-His) |
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PV266482 | ABM | 500 ng | EUR 723.6 |
ERCC1 Protein Vector (Rat) (pPB-N-His) |
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PV266483 | ABM | 500 ng | EUR 723.6 |
ERCC1 Protein Vector (Rat) (pPM-C-His) |
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PV266485 | ABM | 500 ng | EUR 723.6 |
ERCC2 Protein Vector (Rat) (pPB-C-His) |
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PV266486 | ABM | 500 ng | EUR 1399.2 |
ERCC2 Protein Vector (Rat) (pPB-N-His) |
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PV266487 | ABM | 500 ng | EUR 1399.2 |
ERCC2 Protein Vector (Rat) (pPM-C-His) |
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PV266489 | ABM | 500 ng | EUR 1399.2 |
ERCC3 Protein Vector (Rat) (pPB-C-His) |
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PV266490 | ABM | 500 ng | EUR 1399.2 |
ERCC3 Protein Vector (Rat) (pPB-N-His) |
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PV266491 | ABM | 500 ng | EUR 1399.2 |
ERCC3 Protein Vector (Rat) (pPM-C-His) |
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PV266493 | ABM | 500 ng | EUR 1399.2 |
ERCC5 Protein Vector (Rat) (pPB-C-His) |
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PV266494 | ABM | 500 ng | EUR 1399.2 |
ERCC5 Protein Vector (Rat) (pPB-N-His) |
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PV266495 | ABM | 500 ng | EUR 1399.2 |
ERCC5 Protein Vector (Rat) (pPM-C-His) |
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PV266497 | ABM | 500 ng | EUR 1399.2 |
ERCC6 Protein Vector (Rat) (pPB-C-His) |
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PV266498 | ABM | 500 ng | EUR 1429.2 |
ERCC6 Protein Vector (Rat) (pPB-N-His) |
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PV266499 | ABM | 500 ng | EUR 1429.2 |
ERCC6 Protein Vector (Rat) (pPM-C-His) |
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PV266501 | ABM | 500 ng | EUR 1429.2 |
ERCC8 Protein Vector (Rat) (pPB-C-His) |
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PV266502 | ABM | 500 ng | EUR 723.6 |
ERCC8 Protein Vector (Rat) (pPB-N-His) |
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PV266503 | ABM | 500 ng | EUR 723.6 |
ERCC8 Protein Vector (Rat) (pPM-C-His) |
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PV266505 | ABM | 500 ng | EUR 723.6 |
Rat Sterol Carrier Protein 2 (SCP2) Protein |
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20-abx650204 | Abbexa |
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Rat Sterol Carrier Protein 2 (SCP2) Protein |
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abx650204-100g | Abbexa | 100 µg | EUR 500 |
Rat Sterol Carrier Protein 2 (SCP2) Protein |
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abx650204-10g | Abbexa | 10 µg | EUR 200 |
Rat Sterol Carrier Protein 2 (SCP2) Protein |
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abx650204-50g | Abbexa | 50 µg | EUR 350 |
Rat Mucin 2 (MUC2) Protein |
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20-abx654406 | Abbexa |
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Rat Fibrinogen Like Protein 2 (FGL2) Protein |
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20-abx066585 | Abbexa |
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Rat Fibrinogen Like Protein 2 (FGL2) Protein |
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abx066585-100g | Abbexa | 100 µg | EUR 587.5 |
Rat Fibrinogen Like Protein 2 (FGL2) Protein |
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abx066585-10g | Abbexa | 10 µg | EUR 225 |
Rat Fibrinogen Like Protein 2 (FGL2) Protein |
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abx066585-50g | Abbexa | 50 µg | EUR 400 |
Rat Period Circadian Protein 2 (PER2) Protein |
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20-abx165967 | Abbexa |
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Rat Period Circadian Protein 2 (PER2) Protein |
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abx165967-100g | Abbexa | 100 µg | EUR 587.5 |
Rat Period Circadian Protein 2 (PER2) Protein |
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abx165967-10g | Abbexa | 10 µg | EUR 225 |
Rat Period Circadian Protein 2 (PER2) Protein |
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abx165967-50g | Abbexa | 50 µg | EUR 400 |
Rat Mucin-2 (MUC2) Protein |
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abx654406-1g | Abbexa | 1 µg | EUR 225 |
Rat Mucin-2 (MUC2) Protein |
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abx654406-50g | Abbexa | 50 µg | EUR 562.5 |
Rat Mucin-2 (MUC2) Protein |
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abx654406-5g | Abbexa | 5 µg | EUR 387.5 |
Rat Anterior Gradient Protein 2 (AGR2) Protein |
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20-abx065387 | Abbexa |
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Rat Anterior Gradient Protein 2 (AGR2) Protein |
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abx065387-100g | Abbexa | 100 µg | EUR 475 |
Rat Anterior Gradient Protein 2 (AGR2) Protein |
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abx065387-10g | Abbexa | 10 µg | EUR 200 |
Rat Anterior Gradient Protein 2 (AGR2) Protein |
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abx065387-50g | Abbexa | 50 µg | EUR 337.5 |
Rat Bone Morphogenetic Protein 2 (BMP2) Protein |
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20-abx065569 | Abbexa |
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Rat Bone Morphogenetic Protein 2 (BMP2) Protein |
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abx065569-100g | Abbexa | 100 µg | EUR 550 |
Rat Bone Morphogenetic Protein 2 (BMP2) Protein |
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abx065569-10g | Abbexa | 10 µg | EUR 212.5 |
Rat Bone Morphogenetic Protein 2 (BMP2) Protein |
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abx065569-50g | Abbexa | 50 µg | EUR 387.5 |
Rat Keratin 2 (KRT2) Protein |
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20-abx067619 | Abbexa |
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Rat Keratin 2 (KRT2) Protein |
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20-abx067620 | Abbexa |
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Rat Relaxin 2 (RLN2) Protein |
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20-abx068857 | Abbexa |
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Rat Nidogen 2 (NID2) Protein |
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20-abx654562 | Abbexa |
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Rat Relaxin 2 (RLN2) Protein |
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abx068857-10g | Abbexa | 10 µg | EUR 6050 |
Rat Relaxin 2 (RLN2) Protein |
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abx068857-2g | Abbexa | 2 µg | EUR 2412.5 |
Rat Keratin 2 (KRT2) Protein |
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abx067619-100g | Abbexa | 100 µg | EUR 4912.5 |
Rat Keratin 2 (KRT2) Protein |
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abx067619-200g | Abbexa | 200 µg | Ask for price |
Rat Keratin 2 (KRT2) Protein |
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abx067619-50g | Abbexa | 50 µg | EUR 1962.5 |
Rat Keratin 2 (KRT2) Protein |
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abx067620-100g | Abbexa | 100 µg | EUR 362.5 |
Rat Keratin 2 (KRT2) Protein |
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abx067620-200g | Abbexa | 200 µg | EUR 512.5 |
Rat Keratin 2 (KRT2) Protein |
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abx067620-50g | Abbexa | 50 µg | EUR 212.5 |
Rat Nidogen 2 (NID2) Protein |
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abx654562-100g | Abbexa | 100 µg | EUR 475 |
Rat Nidogen 2 (NID2) Protein |
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abx654562-10g | Abbexa | 10 µg | EUR 337.5 |
Rat Nidogen 2 (NID2) Protein |
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abx654562-2g | Abbexa | 2 µg | EUR 200 |
Rat Sirtuin 2 (SIRT2) Protein |
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20-abx069101 | Abbexa |
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Rat Spondin 2 (SPON2) Protein |
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20-abx069152 | Abbexa |
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Rat Arginase 2 (ARG2) Protein |
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20-abx065456 | Abbexa |
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Rat Fibulin 2 (FBLN2) Protein |
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20-abx066639 | Abbexa |
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Rat Chimerin 2 (CHN2) Protein |
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20-abx168958 | Abbexa |
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Rat Galectin 2 (GAL2) Protein |
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20-abx167696 | Abbexa |
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Rat Chimerin 2 (CHN2) Protein |
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abx168958-1ml | Abbexa | 1 ml | EUR 237.5 |
Rat Arginase 2 (ARG2) Protein |
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abx065456-100g | Abbexa | 100 µg | EUR 575 |
Rat Arginase 2 (ARG2) Protein |
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abx065456-10g | Abbexa | 10 µg | EUR 225 |
Rat Arginase 2 (ARG2) Protein |
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abx065456-50g | Abbexa | 50 µg | EUR 400 |
Rat Sirtuin 2 (SIRT2) Protein |
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abx069101-10g | Abbexa | 10 µg | EUR 262.5 |
Rat Sirtuin 2 (SIRT2) Protein |
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abx069101-50g | Abbexa | 50 µg | EUR 487.5 |
Rat Spondin 2 (SPON2) Protein |
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abx069152-1g | Abbexa | 1 µg | EUR 225 |
Rat Spondin 2 (SPON2) Protein |
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abx069152-50g | Abbexa | 50 µg | EUR 562.5 |
Rat Spondin 2 (SPON2) Protein |
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abx069152-5g | Abbexa | 5 µg | EUR 387.5 |
Rat Fibulin 2 (FBLN2) Protein |
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abx066639-100g | Abbexa | 100 µg | EUR 612.5 |
Rat Fibulin 2 (FBLN2) Protein |
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abx066639-10g | Abbexa | 10 µg | EUR 237.5 |
Rat Fibulin 2 (FBLN2) Protein |
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abx066639-50g | Abbexa | 50 µg | EUR 425 |
Rat Syndecan 2 (SDC2) Protein |
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abx653715-5g | Abbexa | 5 µg | EUR 2512.5 |
Rat Angiopoietin Like Protein 2 (ANGPTL2) Protein |
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20-abx065330 | Abbexa |
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Rat Angiopoietin Like Protein 2 (ANGPTL2) Protein |
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20-abx065331 | Abbexa |
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Rat Transferrin Receptor Protein 2 (TFR2) Protein |
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abx167616-100l | Abbexa | 100 µl | EUR 225 |
Rat Transferrin Receptor Protein 2 (TFR2) Protein |
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abx167616-1ml | Abbexa | 1 ml | EUR 575 |
Rat Transferrin Receptor Protein 2 (TFR2) Protein |
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abx167616-200l | Abbexa | 200 µl | EUR 400 |
Rat Metastasis Associated Protein 2 (MTA2) Protein |
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20-abx654354 | Abbexa |
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Rat Metastasis Associated Protein 2 (MTA2) Protein |
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abx654354-10g | Abbexa | 10 µg | EUR 1800 |
Rat Metastasis Associated Protein 2 (MTA2) Protein |
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abx654354-50g | Abbexa | 50 µg | EUR 4525 |
Rat Urocortin 2 (UCN2) Protein |
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20-abx069609 | Abbexa |
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Rat Presenilin 2 (PS2) Protein |
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20-abx654797 | Abbexa |
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Rat Urocortin 2 (UCN2) Protein |
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abx069609-25mg | Abbexa | 25 mg | EUR 400 |
Rat Urocortin 2 (UCN2) Protein |
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abx069609-5mg | Abbexa | 5 mg | EUR 225 |
Rat Presenilin 2 (PS2) Protein |
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abx654797-100g | Abbexa | 100 µg | EUR 4525 |
Rat Presenilin 2 (PS2) Protein |
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abx654797-50g | Abbexa | 50 µg | EUR 1800 |
Rat Microtubule Associated Protein 2 (MAP2) Protein |
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20-abx068014 | Abbexa |
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Rat Membrane Protein, Palmitoylated 2 (MPP2) Protein |
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20-abx654340 | Abbexa |
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Rat Membrane Protein, Palmitoylated 2 (MPP2) Protein |
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abx654340-10g | Abbexa | 10 µg | EUR 4525 |
Rat Membrane Protein, Palmitoylated 2 (MPP2) Protein |
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abx654340-2g | Abbexa | 2 µg | EUR 1800 |
Rat Prokineticin 2 (PK2) Protein |
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20-abx068685 | Abbexa |
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Human N-ERC/Mesothelin ELISA Kit |
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EH3414 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
The event of the ontology and its foremost ideas is described intimately (i.e., the conceptualization of benchmarking occasions, questionnaires, IT providers, indicators and their values) along with its alignment with the DOLCE-UltraLite foundational ontology.
Rat Cholesterol ELISA ELISA | |||
E01A11128 | |||
Goat Cholesterol ELISA ELISA | |||
E01A46041 | |||
Mouse Cholesterol ELISA ELISA | |||
E01A19869 |